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Lung Cancer News
Iressa as Good as Chemotherapy for Lung Cancer (HealthDay)
21 Nov 2008 at 10:48pm
HealthDay - FRIDAY, Nov. 21 (HealthDay News) -- The cancer-fighting pill Iressa works as well as chemotherapy as a second-line treatment for lung cancer, researchers report.

Health Highlights: Nov. 21, 2008 (HealthDay)
21 Nov 2008 at 10:48pm
HealthDay - Here are some of the latest health and medical news developments, compiled by editors of HealthDay:

Smokeout '08: The Perfect Time to Quit (HealthDay)
20 Nov 2008 at 10:49pm
HealthDay - WEDNESDAY, Nov. 19 (HealthDay News) -- Everyone knows smoking is bad for you. Really bad.

Health Highlights: Nov. 20, 2008 (HealthDay)
20 Nov 2008 at 10:49pm
HealthDay - Here are some of the latest health and medical news developments, compiled by editors of HealthDay:

Pill as good as chemo on lung cancer, but costlier (AP)
20 Nov 2008 at 6:51pm
AP - Some advanced lung cancer patients already treated with chemotherapy might be able to skip some of the bad side effects of another series of chemo by taking a pill instead, a study suggests. An international study showed patients on Iressa, an expensive, newer targeted treatment, survived about as long as those on another course of chemotherapy.

Lung cancer pill may get second chance after tests (Reuters)
20 Nov 2008 at 5:32pm
Reuters - The lung cancer pill Iressa has shown surprising results for patients with advanced disease where it has been at least as effective as a standard chemotherapy treatment, researchers reported on Thursday.

Airway Transplant Aided by Stem Cells a Medical First (HealthDay)
19 Nov 2008 at 10:47pm
HealthDay - TUESDAY, Nov. 18 (HealthDay News) -- In a medical first, a 30-year-old mother of two has successfully undergone the first transplantation of a breathing passage fashioned from a donor's airway and her own stem cells, researchers report.

Genetic Trait Could Predict Lung Cancer (HealthDay)
18 Nov 2008 at 10:48pm
HealthDay - TUESDAY, Nov. 18 (HealthDay News) -- Canadian scientists may have discovered a genetic trait that could provide an early indication of which former smokers will develop lung cancer.

Cancer Drug Ups Risk of Clots in Veins (HealthDay)
18 Nov 2008 at 10:48pm
HealthDay - TUESDAY, Nov. 18 (HealthDay News) -- The widely used cancer drug Avastin appears to be associated with a greater risk of developing blood clots in the veins of patients with a variety of cancers.

Stay Upbeat, Exercise to Help Prevent Cancer in Old Age (HealthDay)
17 Nov 2008 at 10:47pm
HealthDay - MONDAY, Nov. 17 (HealthDay News) -- How you live affects your chances of developing cancer after age 65, new research finds.

Statewide Smoking Ban Considered
22 Nov 2008 at 12:06am

Thirty cities in Mississippi have smoking bans in place. There is a push now for a statewide ban.



Lung Cancer Needs Awareness Too
21 Nov 2008 at 7:47pm

Lung cancer kills more than four times as many Americans as breast cancer. But while pink ribbons trumpet Breast Cancer Awareness Month throughout October, little attention is paid to lung cancer in November, ...



Smoking's Many Myths Examined
21 Nov 2008 at 3:33pm

Christopher Wanjek is the author of the books "Bad Medicine" and "Food At Work." His Bad Medicine column appears each Tuesday on LiveScience.



Stoical patients leave it too late to see GPs for cancer checks,...
21 Nov 2008 at 10:51am

Nearly 11,000 cancer deaths could be avoided every year if British doctors were as good at detecting and treating the disease as the best countries in Europe and patients were less stoical, according to data ...



Cancer Drug Avastin Raised Risk Of Blood Clots, Study
21 Nov 2008 at 6:05am

Featured Article Main Category: Cancer / Oncology Also Included In: Blood / Hematology ; Cardiovascular / Cardiology ; Clinical Trials / Drug Trials Article Date: 19 Nov 2008 - 8:00 PST A new analysis of ...



Blood Clots in Cancer Patients
21 Nov 2008 at 1:42am

A drug meant to inhibit tumor growth may have a dangerous side effect. Bevacizumab is prescribed to patients with colorectal cancer, non?small cell lung cancer , renal cell cancer and breast cancer to inhibit ...



Pill as good as chemo on lung cancer, but costlier
20 Nov 2008 at 9:16pm

Some advanced lung cancer patients already treated with chemotherapy might be able to skip some of the bad side effects of another series of chemo by taking a pill instead, a study suggests.



Tri-Cities Cancer Center Encouraging Lung Cancer Awareness
20 Nov 2008 at 5:06pm

As part of Lung Cancer Awareness Month, health professionals at the Tri-Cities Cancer Center are encouraging people to educate themselves about the warning signs.



PharmaMar Receives "Supporting A Cure In Our Time" Sarcoma Foundation ...
20 Nov 2008 at 12:52pm

PharmaMar has received the Award "Supporting A Cure In Our Time" from the Sarcoma Foundation of America for its "support in the search for an effective cure for soft tissue sarcomas," goal of the foundation, ...



Higher Risk Of Certain Cancers Recorded In HIV-Positive People
20 Nov 2008 at 8:26am

Physicians in the U.S. are reporting a higher risk for certain types of cancers -- such as liver, head, neck and lung -- in people living with HIV/AIDS, raising concerns that a cancer epidemic is imminent in ...



Amgen, Takeda Suspend Enrollment In a Lung-cancer-drug Study
20 Nov 2008 at 3:50am

These gains don't cause pain. A capital gain is the amount of money you pocket by selling one of your investments for more than you paid for it.



Helix BioPharma Presents Preclinical L-DOS47 Data at The Second...
19 Nov 2008 at 11:30pm

Helix BioPharma Corp. today announced that it will present preclinical data about the mechanism of action for L-DOS47, the first drug candidate under development based on the Company's DOS47 technology, at The ...



Smokeout '08: The Perfect Time to Quit
19 Nov 2008 at 7:06pm

Everyone knows smoking is bad for you. Really bad. But just last week, the U.S. Centers for Disease Control and Prevention said that the United States won't meet the Healthy People 2010 objective of reducing ...



New Weapon In Fight Against Lung Cancer
19 Nov 2008 at 2:40pm

Content courtesy of Ivanhoe November is lung cancer awareness month, a time to take a closer look at the disease that kills more people than any other kind of cancer.



Stay Upbeat, Exercise to Help Prevent Cancer in Old Age
19 Nov 2008 at 10:09am

How you live affects your chances of developing cancer after age 65, new research finds.



Pill As Good As Chemo on Lung Cancer, But Costlier - November 21, 2008
21 Nov 2008 at 11:30pm
... Pill As Good As Chemo on Lung Cancer, But Costlier LONDON (AP) -- Some advanced lung cancer patients already treated with chemotherapy might be able to skip some of the bad ...

School neglects smoking policies
21 Nov 2008 at 11:30pm
... that, backed up by "overwhelming scientific evidence," exposure to secondhand smoke causes heart disease, lung cancer and respiratory problems. Approximately 3,000 American nonsmokers die from lung cancer every year thanks ...

Iressa as good as chemotherapy for lung cancer
21 Nov 2008 at 11:30pm
... as chemotherapy as a second-line treatment for lung cancer, researchers report. Although neither therapy prolongs ... assistant professor at the M. D. Anderson Cancer Center in Houston. This finding should reassure ...

Study: Pill as good as chemo for some...
21 Nov 2008 at 10:30pm
... specialist at the Dana-Farber Cancer Institute in Boston, Massachusetts, who was not ... the International Association for the Study of Lung Cancer Research and also was not involved ...

Could lawmakers ban smoking statewide?
21 Nov 2008 at 9:28pm
... place state wide. "Generally we choose restaurants that are smoke free," said Jeanette Gossett, lung cancer survivor. Meridian resident Jeanette Gossett knows the dangers of smoking and second hand smoke. ...

Pill as good as chemo on lung cancer
21 Nov 2008 at 9:26pm
... Pill as good as chemo on lung cancer Some advanced lung cancer patients already treated with chemotherapy might be able to skip ...

Death is a hot topic for writers these days.
21 Nov 2008 at 8:58pm
... twist of fate was diagnosed with brain cancer not long after Barnes' book was published, ... apotheosis. Critic John Leonard, who died of lung cancer on Nov. 5, wrote in the ...

Man Says His Dog Detected His Skin Cancer
21 Nov 2008 at 8:31pm
... cancerous mole removed. Malignant melanoma is a cancer that grows in skin cells called melanocytes. ... showed that dogs can detect breast and lung cancer with sensitivity and specificity between 88 ...

Pill That Reduces the Second Chemotherapy Ordeal
21 Nov 2008 at 8:31pm
... III clinical trial, led by researchers at The University of Texas M. D. Anderson Cancer Center, advanced lung cancer patients already treated with chemotherapy might be able to skip some of the ...

To smoke, or not to smoke?
21 Nov 2008 at 8:02pm
... COMTEX) -- -- On Thursday, the American Cancer Society held its 33rd Great American Smokeout, ... I'll quit someday. I've lost family to lung cancer. It's just something to do right ...

Landmark ruling for asbestos victims
21 Nov 2008 at 7:28pm
... Thousands of victims of asbestos-related cancer and their families won a test case ... family of Charles O'Farrell, who died from mesothelioma in 2003, won a court judgment for ...

Pill Could Help Cut Down On Chemo Effects
21 Nov 2008 at 7:25pm
... Topping tonight's "Health Headlines", some advanced lung cancer patients already treated with chemotherapy may actually be able to skip the bad side ...

News Review: Science battles to keep up with patients' hopes
21 Nov 2008 at 7:03pm
... cell development. She would have lost a lung if scientists had not taken part of ... cause more harm than good, for example cancer, I believe that we are close to ...

Group pushes legislature for statewide smoking ban
21 Nov 2008 at 6:34pm
... resident Jeanette Gossett knows the dangers of smoking and second hand smoke. As a lung cancer survivor, she now tries to stay away from both. "I have a son who ...

Pill as good as chemo on lung cancer, but costlier
21 Nov 2008 at 6:34pm
... Pill as good as chemo on lung cancer, but costlier Story Published: Nov 21, ... PST LONDON (AP) - Some advanced lung cancer patients already treated with chemotherapy might be ...

Oral Gefitinib As Effective As Injected Docetaxel For Survival Of Patients Wi...
21 Nov 2008 at 4:00am
Gefitnib is as effective a second-line treatment as docetaxel for patients with non-small cell* lung cancer. The INTEREST study, published in an Article in this week's edition of The Lancet, thus establishes gefitinib as a valid treatment option for people with this condition. The study was written by Dr Edward Kim, M. D. Anderson Cancer Center, Houston, Texas, USA and colleagues.

Amgen, Takeda And Millennium Provide Update On Phase 3 Trial Of Motesanib In ...
21 Nov 2008 at 2:00am
Amgen (Nasdaq: AMGN) and Millennium: The Takeda Oncology Company, a subsidiary of Takeda Pharmaceutical Company Limited (TSE: 4052), announced that enrollment in the Phase 3 MONET1 trial evaluating motesanib (AMG 706) in combination with paclitaxel and carboplatin for the first-line treatment of advanced non-small cell lung cancer (NSCLC) has been temporarily suspended following a planned safety data review of 600 patients by the study's independent Data Monitoring Committee (DMC).

Lung Cancer Risk In Smokers May Be Lowered By Broccoli
19 Nov 2008 at 6:00am
The cancer preventive properties of broccoli and other cruciferous vegetables appear to work specifically in smokers, according to data presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research.

Why Only Some Former Smokers Develop Lung Cancer
18 Nov 2008 at 7:00am
Canadian researchers are trying to answer why some smokers develop lung cancer while others remain disease free, despite similar lifestyle changes. Results were presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research. According to the Centers for Disease Control and Prevention, more people die from lung cancer than any other cancer type.

Extending Chemotherapy Improves Control Of Lung Cancer
18 Nov 2008 at 5:00am
A new Australian study has found that extending the use of chemotherapy in patients with advanced non-small cell lung cancer better controls the disease, as well as providing a modest improvement in survival. The study will be reported today (18/11) to the Clinical Oncolgoical Society of Australia Annual Scientific Meeting in Sydney.

First Pivotal Trials Begin For Boehringer Ingelheim's Novel Triple Angiokinas...
17 Nov 2008 at 4:00am
Boehringer Ingelheim has marked a new milestone within its rapidly expanding oncology portfolio with the announcement today that the company has progressed another of its oncology compounds into pivotal phase III clinical development.

In Determining Overall Survival Of Lung Cancer Patients, Gender Is Key
14 Nov 2008 at 9:00am
Even though some combinations of gender, race and/or marital status can factor into the overall survival of nonoperative non-small cell lung cancer patients, gender is the most significant factor impacting overall survival, according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, sponsored by ASTRO, ASCO, IASLC and the University of Chicago.

Research Demonstrating Differing Genetic Makeup Of Lung Cancer In AfricanAmer...
14 Nov 2008 at 8:00am
The tumors of African-American non-small cell lung cancer patients are more likely to carry a higher number of copies of the epidermal growth factor receptor (EGFR) gene and fewer mutations of EGFR itself than Caucasians according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, cosponsored by ASTRO, ASCO, IASLC and the University of Chicago.

Proton Therapy May Reduce Serious Side Effect Of Lung Cancer Treatment
14 Nov 2008 at 8:00am
Patients with locally advanced lung cancer who receive chemotherapy and proton therapy, a specialized form a radiation therapy only available in a few centers in the United States, have fewer instances of a serious side effect called bone marrow toxicity than patients who receive chemotherapy

Study First To Combine 2 Chemotherapies And 2 Targeted Therapies
14 Nov 2008 at 7:00am
The four drug-combination of carboplatin and paclitaxel, with the targeted therapies bevacizumab (Avastin) and cetuximab (Erbitux), is safe and may improve survival for patients with advanced lung cancer, according to a cooperative group study led by The University of Texas M. D. Anderson Cancer Center.

Overall Survival In 1st-line NSCLC Reaches 15 Months With Erbitux, Merck Serr...
14 Nov 2008 at 6:00am
Data presented today at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology show that patients with non-small cell lung cancer (NSCLC) who were given Erbitux® (cetuximab) in addition to a standard 1st-line platinum-based chemotherapy lived significantly longer than those who received chemotherapy alone.1 This effect was more pronounced in patients treated with Erbitux who developed early acne-like rash, resulting in median overall survival of 15 months.

Bone Marrow Toxicity In Advanced Lung Cancer May Be Reduced By Proton Therapy...
14 Nov 2008 at 5:00am
Patients treated for locally advanced non-small cell lung cancer who receive chemotherapy and proton beam therapy have fewer instances of bone marrow toxicity than patients who receive the standard treatment of intensity-modulated radiation (IMRT) and concurrent chemotherapy, according to researchers from The University of Texas M. D. Anderson Cancer Center.

Large International Study Identifies Genetic Susceptibility To Lung Cancer
13 Nov 2008 at 10:00am
In a paper to be published in Nature Genetics on 2nd November, a worldwide consortium of investigators present a major breakthrough for understanding the genetic basis of lung cancer. The results are based on the largest genetic study of lung cancer ever conducted, and was organised by the International Agency for Research on Cancer (IARC, Lyon, France), the Centre National de Génotypage (CNG, Evry, France), with support from the Institut National du Cancer (Paris, France).

Phase 2 Study Of IMC-1121B In First-Line Treatment Of Advanced Non-Small Cell...
13 Nov 2008 at 6:00am
ImClone Systems Incorporated (NASDAQ: IMCL), a global leader in the development and commercialization of novel antibodies to treat cancer, today announced that its disease-directed Phase 2 clinical trial of IMC-1121B in combination with paclitaxel and carboplatin as first-line therapy in advanced non-small cell lung cancer (NSCLC) has opened for patient enrollment. IMC-1121B is ImClone's proprietary fully human, IgG1 anti-vascular growth factor receptor-2 (VEGFR-2) monoclonal antibody.

Lung Cancer Rates Dropping But Hospitalization Rates Remain Constant, USA
13 Nov 2008 at 4:00am
Hospital admissions for lung cancer remained relatively stable - at roughly 150,000 a year between 1995 and 2006 - despite a steady decline in the number of Americans diagnosed with the disease, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

Why only some former smokers develop lung cancer
17 Nov 2008 at 10:22pm
Canadian scientists are trying to answer why some smokers develop lung cancer while others remain disease free, despite similar changes in lifestyle. Results were presented at the American Association for Cancer Research's Seventh Annual International Conference on Frontiers in Cancer Prevention Research........

Proton therapy and concurrent chemotherapy in lung cancer
17 Nov 2008 at 10:22pm
Patients treated for locally advanced non-small cell lung cancer who receive chemotherapy and proton beam treatment have fewer instances of bone marrow toxicity than patients who receive the standard therapy of intensity-modulated radiation (IMRT) and concurrent chemotherapy, as per scientists from The University of Texas M. D. Anderson Cancer Center........

Study finds that practice makes perfect in lung cancer surgery
17 Nov 2008 at 10:22pm
Patients operated on by surgeons who do not routinely remove cancer from the lungs may be at a higher risk for complications, as per a research studyconducted by scientists at Duke University Medical Center. "Our study observed that hospitals that do higher volumes of these types of surgeries have correspondingly lower mortality rates than those who do fewer of the procedures," said Andrew Shaw, M.D., an anesthesiologist at Duke and lead investigator on the study........

Novel Lung Cancer Vaccine Trial Launched
17 Nov 2008 at 10:22pm
Oncologists at the Moores Cancer Center at the University of California, San Diego (UCSD) in La Jolla are hoping to stave off the relentless march of advanced lung cancer by treating patients with a novel kind of cancer vaccine. While a number of vaccines attempt to pump up the immune system to fight off a cancer, the new vaccine, Lucanix, is genetically engineered to also trick the cancer into turning off its immune system-suppressing activities........

Less nicotine to the brain than regular cigarettes?
17 Nov 2008 at 10:22pm
For decades now, cigarette makers have marketed so-called light cigarettes which contain less nicotine than regular smokes with the implication that they are less harmful to smokers' health. A new UCLA study shows, however, that they deliver nearly as much nicotine to the brain. Reporting in the current online edition of the International Journal of Neuropsychopharmacology, UCLA psychiatry professor Dr. Arthur L. Brody and his colleagues observed that low-nicotine cigarettes act similarly to regular cigarettes, occupying a significant percentage of the brain's nicotine receptors........

Physicians may miss opportunities to respond with empathy
17 Nov 2008 at 10:22pm
In a small study of 20 audiorecorded interactions, physicians seldom responded empathetically to concerns raised by lung cancer patients, as per a report in the September 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. "Empathy is an important element of effective communication between patients and physicians and is linked to improved patient satisfaction and compliance with recommended therapy," the authors write as background information in the article. "Patients who are more satisfied with the communication in their medical encounters have improved understanding of their condition, with less anxiety and improved mental functioning." However, responding to patients' emotional needs can be challenging for physicians; they may begin medical school with empathy for their patients but gradually learn detachment, perhaps in order to cope with time constraints or sadness........

Pazopanib shrinks lung cancers before surgery
17 Nov 2008 at 10:22pm
Pazopanib, a new oral angiogenesis inhibitor, has demonstrated interesting activity in difficult to treat non-small-cell lung cancer, US scientists report. In a phase II trial, 30 out of 35 patients treated with preoperative pazopanib for a minimum of two weeks saw their tumor size shrink by up to 85%........

Common gene disorder doubles risk of lung cancer
17 Nov 2008 at 10:22pm
Mayo Clinic scientists have observed that carrying a common genetic disorder doubles the risk of developing lung cancer in smokers and nonsmokers. The study is reported in the May 26 issue of the Archives of Internal Medicine, a journal published by the American Medical Association. Scientists observed that the genetic disorder, alpha-1 antitrypsin deficiency (1ATD), could explain up to about 12 percent of patients with lung cancer in this study and likely represents the same widespread risk in the general population. "This is a seriously underdiagnosed disorder and suggests that people who have lung cancer and chronic obstructive pulmonary diseases (COPD) in their families should be screened for these gene carriers," says Ping Yang, M.D., Ph.D., a Mayo Clinic epidemiologist and lead investigator on the study........

Determining genetic signature of lung tumors
17 Nov 2008 at 10:22pm
The first U.S. clinical trial using genetic screening to identify lung tumors likely to respond to targeted therapies supports the use of those drugs as first-line therapy rather than after standard chemotherapy has failed. While the study led by Massachusetts General Hospital Cancer Center researchers observed that upfront gefitinib (Iressa) therapy considerably improved the outcomes for non-small-cell-lung-cancer (NSCLC), additional research is mandatory before such a strategy can be used for routine therapy planning. The report appears in the May 20 Journal of Clinical Oncology........

Mouth may tell the tale of lung damage
17 Nov 2008 at 10:22pm
Cells lining the mouth reflect the molecular damage that smoking does to the lining of the lungs, scientists at The University of Texas M. D. Anderson Cancer Center report today at the annual meeting of the American Association for Cancer Research. Examining oral tissue lining the mouth to gauge cancer-inducing molecular alterations in the lungs could spare patients and those at risk of lung cancer from more invasive, uncomfortable procedures used now, said senior researcher Li Mao, M.D., professor in M. D. Anderson's Department of Thoracic/Head and Neck Medical Oncology........

PET Outperforms CT In Malignant Lung Nodules
17 Nov 2008 at 10:22pm
Scientists involved in a large, multi-institutional study comparing the accuracy of positron emission tomography (PET) and computed tomography (CT) in the characterization of lung nodules observed that PET was far more reliable in detecting whether or not a nodule was cancerous. "CT and PET have been widely used to characterize solitary pulmonary nodules (SPNs) as non-malignant or cancerous," said James W. Fletcher, professor of radiology at Indiana University School of Medicine in Indianapolis, Ind. "Almost all prior studies examining the accuracy of CT for characterizing lung nodules, however, were performed more than 15 years ago with outdated technology and methods, and prior PET studies were limited by small sample sizes," he noted........

Number of Russian women smokers has doubled
17 Nov 2008 at 10:22pm
In 1992, seven per cent of women smoked, in comparison to almost 15 per cent by 2003. In the same period, the number of men who smoke has risen from 57 per cent to 63 per cent. The scientists behind the study, reported in the journal Tobacco Control, blame the privatisation of the previously state owned tobacco industry and the behaviour of the transnational tobacco companies (TTCs) for what they describe as a "very worrying increase"........

Diet, gardening and lung cancer risk
17 Nov 2008 at 10:22pm
By simply eating four or more servings of green salad a week and working in the garden once or twice a week, smokers and nonsmokers alike may be able to substantially reduce the risk of developing lung cancer, say scientists at The University of Texas M. D. Anderson Cancer Center. "This is the first risk prediction model to examine the effects of diet and physical activity on the possibility of developing lung cancer," says Michele R. Forman, Ph.D., lead author of the study and a professor in M. D. Anderson's Department of Epidemiology. Forman presented study results at the American Association for Cancer Research "Frontiers in Cancer Prevention Research" meeting Dec. 7 in Philadelphia, Pa. The data are from an ongoing M. D. Anderson case-control lung cancer study involving more than 3,800 participants. Separate epidemiologic risk assessment models were developed for current and former smokers as well as for those who have never smoked ("never smokers")........

Quit Rates Double With Counseling And Free Nicotine Patches
17 Nov 2008 at 10:22pm
Increasing the level of Quitline smoking cessation services and offering free nicotine patches are a successful and cost-effective way to reduce smoking rates, as per two new studies in the recent issue of Tobacco Control, a peer-evaluated publication of the British Medical Journal. Both studies were conducted by scientists at Kaiser Permanentes Center for Health Research in Portland, the Oregon Health Department, and Free and Clear in Seattle, a phone-based tobacco therapy program........

PET scanning for lung cancer staging
17 Nov 2008 at 10:22pm
Positron emission tomography (PET) is a useful diagnostic tool that supports the need for more accurate staging of lung cancer and improved therapy for patients, concludes an extensive systematic review published online today in Journal of National Cancer Institute. The review conducted by the Lung Cancer Disease Site Group of Cancer Care Ontarios Program in Evidence-Based Care led by a Sunnybrook researcher, Dr. Yee Ung, evaluates the accuracy and utility of 18-fluorodeoxyglucose PET (18FDG-PET) in the diagnosis and staging of lung cancer........

Lung airway cells activate vitamin D
4 Nov 2008 at 10:56pm
Vitamin D is essential to good health but needs to be activated to function properly in the human body. Until recently, this activation was thought to happen primarily in the kidneys, but a new University of Iowa study finds that the activation step can also occur in lung airway cells. The study also links the vitamin D locally produced in the lung airway cells to activation of two genes that help fight infection. The study results appear in the Nov. 15 issue of the Journal of Immunology, now online........

Statins associated with lower risk of death from pneumonia
4 Nov 2008 at 10:56pm
Individuals who take cholesterol-lowering statins before being hospitalized with pneumonia appear less likely to die within 90 days afterward, as per a report in the October 27 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. In the United States and Europe, pneumonia hospitalization rates have increased 20 percent to 50 percent over the past decade, as per background information in the article. About 10 percent to 15 percent of those with pneumonia die from the disease. A recent review article indicated that statins may benefit patients with sepsis (infection of the bloodstream) or bacteremia (presence of bacteria in the bloodstream), possibly due to the medications' anti-clotting, anti-inflammatory or immune-modifying properties........

Hope to emphysema patients
4 Nov 2008 at 10:56pm
Patients in the Valley with emphysema might soon be breathing a little easier thanks to a new airway bypass study called the Exhale Airways Stents for Emphysema (EASE) trial. The trial principal is Dr. Karl Van Gundy aided by researchers Drs. Michael Peterson, Jose Joseph, Timothy Evans and Kathryn Bilello all pulmonologists at UCSF Fresno Medical Education Program. The study is a multi-center, international trial that is designed to evaluate the safety and effectiveness of this new and innovative procedure. There are only two other sites administering the trial in California besides UCSF Fresno UC Davis Medical Center and Cedars-Sinai Medical Center in Los Angeles........

Sleep apnea linked to increased risk of death
4 Nov 2008 at 10:56pm
Sleep-disordered breathing (also known as sleep apnea) is linked to an increased risk of death, as per new results from the Wisconsin Sleep Cohort, an 18-year observational study supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health. Scientists observed that adults (ages 30 to 60) with sleep-disordered breathing at the start of the study were two to three times more likely to die from any cause in comparison to those who did not have sleep-disordered breathing. The risk of death was associated with the severity of sleep-disordered breathing and was not attributable to age, gender, body mass index (an indicator of overweight or obesity), or cardiovascular health status........

Men at increased risk of death from pneumonia
4 Nov 2008 at 10:56pm
Men who come to the hospital with pneumonia generally are sicker than women and have a higher risk of dying over the next year, despite aggressive medical care, as per a research studybeing presented Tuesday, May 20, at the 104th International Conference of the American Thoracic Society. Scientific sessions are scheduled May 16 to 21 in Toronto........

Personalized therapy for asthma and COPD
4 Nov 2008 at 10:56pm
Scientists at Washington University School of Medicine in St. Louis have defined a new type of immune response that is activated in patients with severe asthma and COPD (chronic obstructive pulmonary disease). Their discovery could dramatically improve diagnosis and therapy of patients with chronic inflammatory lung disease........

Asthma and Smoker's Lung
4 Nov 2008 at 10:56pm
Dry airways may not only play a central role in the development of the in-herited lung disease cystic fibrosis, but also in much more common ac-quired chronic lung diseases such as asthma and smoker's lung, the ciga-rette smoke-induced chronic obstructive pulmonary disease (COPD). This is the conclusion reached by researchers at Heidelberg University Hospital under the direction of Assistant Professor Dr. Marcus Mall from the Department of Pediatrics at Heidelberg University Hospital and Professor Dr. Richard Boucher of the University of North Carolina at Chapel Hill. In ani-mal studies, they observed that insufficient hydration of the airway surfaces leads to pathologies typical of chronic obstructive lung diseases in humans........

Smokers With Lung Disease Need More
4 Nov 2008 at 10:56pm
OHSU Smoking Cessation Center scientists outline key steps for developing and implementing clinic-based systems to provide smoking cessation therapy tailored to smokers with respiratory disorders. Smokers with lung disease require more than brief smoking cessation interventions to successfully quit, scientists in the Oregon Health and Science University Smoking Cessation Center report........

One cannabis joint equal to up to 5 cigarettes
4 Nov 2008 at 10:56pm
A single cannabis joint has the same effect on the lungs as smoking up to five cigarettes in one go, indicates research published ahead of print in the journal Thorax. The scientists base their findings on 339 adults up to the age of 70, selected from a research study that's ongoing of respiratory health, and categorised into four different groups........

'Healthy' children with smoking parents aren't really so healthy
4 Nov 2008 at 10:56pm
Children of smokers who dont show any signs of respiratory problems may still be experiencing damaging changes in their airways that could lead to lung disease during the later part of life, as per a new study presented at the American Thoracic Society 2007 International Conference, on Sunday, May 20........

Sleep Apnea Patients And Risk Of Car Crashes
4 Nov 2008 at 10:56pm
People with obstructive sleep apnea have a markedly increased risk of severe motor vehicle crashes involving personal injury, as per a research studypresented at the American Thoracic Society 2007 International Conference, on Sunday, May 20. The study of 800 people with sleep apnea and 800 without the nighttime breathing disorder observed that patients with sleep apnea were twice as likely as people without sleep apnea to have a car crash, and three to five times as likely to have a serious crash involving personal injury. Overall, the sleep apnea group had a total of 250 crashes over three years, compared with 123 crashes in the group without sleep apnea........

Breathing for better lung health
4 Nov 2008 at 10:56pm
While working to find novel ways to treat the life-threatening disease of cystic fibrosis, scientists at the University of North Carolina have discovered that the rhythmic motion of the lungs during normal breathing is a critical regulator of the clearance of bacteria and other noxious materials. Their research, funded by the Cystic Fibrosis Foundation and the National Institute of Health, is reported in the latest issue of The Journal of Physiology........

alcohol and sleep-related breathing disorder
4 Nov 2008 at 10:56pm
Increased usual alcohol consumption among men is linked to an increased risk of a mild or worse sleep-related breathing disorder (SRBD), as per a research studyreported in the April 15th issue of the Journal of Clinical Sleep Medicine (JCSM). The study, authored by Paul E. Peppard, PhD, and his colleagues at the University of Wisconsin-Madison, focused on 775 men and 645 women, who were reviewed for alcohol consumption and a sleep-related breathing disorder. It was discovered that, relative to men who consumed less alcohol, for each increment of one drink per day, men who consumed more alcohol had 25 percent greater odds of a mild or worse SRBD........

Bacteria from patient's dental plaque
4 Nov 2008 at 10:56pm
Patients admitted to a hospital's intensive care unit (ICU) already are seriously ill, so the last thing they need is a new infection. Unfortunately, statistics show that as a number of as 25 percent of all patients admitted to the ICU and placed on ventilators develop pneumonia, which can be fatal........

Go To Church To Breathe Easier
4 Nov 2008 at 10:56pm
Going to church might help you breathe easier. A new study by Temple Universitys Joanna Maselko, Sc.D., observed that religious activity may protect and maintain pulmonary health in the elderly. Pulmonary function is an important indicator of respiratory and overall health, yet little is known about the psychosocial factors that might predict pulmonary function. At the same time, religious activity is emerging as a potential health promoting factor, particularly among the elderly. We wanted to determine whether there was a correlation between the two, Maselko said........

Why Only Some Former Smokers Develop Lung Cancer
21 Nov 2008 at 1:00pm
Canadian researchers are trying to answer why some smokers develop lung cancer while others remain disease free, despite similar lifestyle changes.

Dangerous 'Two-faced' Protein Crucial To Breast Cancer Spread And Growth Iden...
21 Nov 2008 at 4:00am
Two critical properties of cancer cells are their ability to divide without restraint and to spread away from the primary tumor to establish new tumor sites. Now, researchers have found a protein they say acts as a deadly master switch, both freeing cancer cells from a tumor while ramping up new growth.

Iressa Proves Just As Effective As Chemotherapy For Lung Cancer
19 Nov 2008 at 11:00pm
Gefitinib, also known as Iressa, the once-promising targeted therapy for the treatment of nonsmall cell lung cancer, has proven as effective as chemotherapy as a second-line therapy for the disease with far fewer side effects, according to an international Phase III clinical trial.

Tumor Environment Determines Whether The Cellular Process Autophagy Enables C...
19 Nov 2008 at 11:00pm
Confusingly, the cellular process autophagy (essentially self-eating) has been implicated in both cancer cell death and survival. New insight into this paradox has now been provided by work which indicates that the context in which the process occurs determines the outcome.

Over-stressing Already Taxed Cancer Cells May Kill Them
19 Nov 2008 at 10:00pm
Cancer cells are already stressed by the fast pace they require to grow and spread and scientists believe a little more stress just may kill them.

Broccoli May Lower Lung Cancer Risk In Smokers
19 Nov 2008 at 1:00pm
The cancer preventive properties of broccoli and other cruciferous vegetables appear to work specifically in smokers, according to new research.

Survival Of Head And Neck Cancer Patients Is Greatly Affected By Coexisting A...
18 Nov 2008 at 11:00pm
Current estimates for head and neck cancer survival are largely inaccurate because they widely disregard many of the most common diseases such patients have in addition to their primary cancer, according to a head and neck specialist.

Repairing DNA Damage: Researchers Discover Critical Process In Cancer Treatment
15 Nov 2008 at 7:00pm
From the sun's UVA rays to tobacco smoke, our environment is chock-full of DNA-damaging agents that can lead to cancer. Thanks to our body's DNA repair mechanisms, however, the effects of many carcinogens can be reversed thereby preventing the formation of tumours. Now, scientists have identified a new biochemical pathway which controls DNA repair.

Gender Is Key Factor In Determining Overall Survival Of Lung Cancer Patients
14 Nov 2008 at 10:00pm
Even though some combinations of gender, race and/or marital status can factor into the overall survival of nonoperative non-small cell lung cancer patients, gender is the most significant factor impacting overall survival, according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, sponsored by ASTRO, ASCO, IASLC and the University of Chicago.

Novel Four-drug Combination Proves Safe For Lung Cancer Treatment
14 Nov 2008 at 10:00am
The four-drug combination of carboplatin and paclitaxel, with the targeted therapies bevacizumab and cetuximab, is safe and may improve survival for patients with advanced lung cancer, according to a new study.

Differing Genetic Makeup Of Lung Cancer In African-American Patients Shown
14 Nov 2008 at 4:00am
The tumors of African-American non-small cell lung cancer patients are more likely to carry a higher number of copies of the epidermal growth factor receptor gene and fewer mutations of EGFR itself than Caucasians according to a new study.

Proton Therapy And Concurrent Chemotherapy May Reduce Bone Marrow Toxicity In...
14 Nov 2008 at 1:00am
Patients treated for locally advanced nonsmall cell lung cancer who receive chemotherapy and proton beam therapy have fewer instances of bone marrow toxicity than patients who receive the standard treatment of intensity-modulated radiation and concurrent chemotherapy, according to researchers.

Chemotherapy Plus Targeted Therapies Shows Improved Survival In Advance-stage...
12 Nov 2008 at 11:00pm
The combination of traditional chemotherapy agents with targeted therapies called monoclonal antibodies showed no safety concerns and improved survival in patients with advanced non-small cell lung cancer according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, sponsored by ASTRO, ASCO, IASLC and the University of Chicago.

Advanced Lung Cancer Patients See Improved, Progression-free Survival
12 Nov 2008 at 11:00pm
Patients with advanced non-small cell lung cancer whose disease has progressed following chemotherapy have a higher rate of tumor shrinkage and a longer interval before cancer progression when bevacizumab is added to standard second-line erlotinib therapy, according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, sponsored by ASTRO, ASCO, IASLC and the University of Chicago.

Tissue Analyses Indicate Survival Benefits For Some Lung Cancer Patients
12 Nov 2008 at 11:00pm
Taking small tissue samples from patients with lung cancer and examining them under a microscope, a procedure called histology, is now being utilized to better tailor the chemotherapy treatments to improve survival in some patients with non-small cell lung cancer, according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, cosponsored by ASTRO, ASCO, IASLC and the University of Chicago.

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