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6 Oct 2008 at 12:57pm Reuters - Asthma patients who are black tend to have more severe disease than asthma patients who are white, leading to more asthma control problems, higher rates of emergency department visits, and overall worse quality of life. These findings point to genetic differences that lead to poor responses to drug therapy as the source of these racial disparities. 4 Oct 2008 at 12:47am HealthDay - (HealthDay News) -- Having asthma doesn't necessarily mean an unhealthy pregnancy. The key is to control symptoms and prevent attacks. 2 Oct 2008 at 10:46pm HealthDay - THURSDAY, Oct. 2 (HealthDay News) -- Young children who wheeze when they have rhinovirus infection -- the most common cause of colds -- are at much greater risk of developing asthma later during childhood, a new study says. 2 Oct 2008 at 10:46pm HealthDay - THURSDAY, Oct. 2 (HealthDay News) -- The inhaled steroids that are often used to treat asthma don't work as well in the overweight or obese, new research shows. 1 Oct 2008 at 10:58am Reuters - Lab experiments indicate that people with asthma who are overweight or obese have a reduced response to steroid treatment, compared with their lean counterparts. 24 Sep 2008 at 6:07pm Reuters - Swimming in outdoor chlorinated pools appears to increase the odds a child will develop asthma, Belgian researchers said on Thursday. 24 Sep 2008 at 11:29am AFP - The use of a once-a-day inhaler for chronic bronchitis or emphysema for longer than one month increases the risk of heart attack, stroke or cardiovascular death by 58 percent, a new study says. 23 Sep 2008 at 4:07pm AP - Inhaler drugs used by millions of people with emphysema and bronchitis may slightly raise the risk for heart attacks and even death, a study suggests. 19 Sep 2008 at 10:46pm HealthDay - THURSDAY, Sept. 18 (HealthDay News) -- Children given acetaminophen during the first year of life to reduce fever are more likely to develop asthma later on, a new study finds. 19 Sep 2008 at 1:19am Reuters - Infants who have been given the common pain reliever paracetamol may have a higher risk of developing asthma and eczema by the time they are 6 or 7, a large study covering children in 31 countries has found. |
by Malaysian Medical Resources 19 Sep 2008 at 10:00pm Babies Given Acetaminophen More Likely to Develop Asthma, Psoriasis Drug Showing Promise, Diabetes Affects Gastric Bypass Results a Babies Given Acetaminophen More Likely to Develop Asthma, Psoriasis Drug Showing Promise, Diabetes Affects Gastric Bypass Results (Source: Malaysian Medical Resources) by Latest entries from www.anxietyinsights.info 12 Sep 2008 at 3:25am Two to three years after the disaster, psychological trauma and new respiratory problems were still elevated across all groups A new analysis from the World Trade Center Health Registry provides the most comprehensive picture yet of how 9/11 affected enrollees' physical and mental health two to three years after the disaster. The report - released by the Health Department in the Journal of Urban Health, also includes the first estimates of respiratory health problems among lower Manhattan workers and residents from the registry, indicating that both groups suffered new cases of asthma. The new analysis examines health effects among all 71,437 participants of the World Trade Center Health Registry - an estimated 17.4% of the people whose exposure to the disaster would have made them eligible to enroll. The registry includes rescue and recovery workers, Lower Manhattan residents, area workers, commuters, and passersby. Overall, half of the registrants reported being in the dust cloud from the collapsing towers; 70% witnessed a traumatic sight, such as a plane hitting the tower; and 13% sustained an injury that day. The survey found that, two to three years after these experiences, 3% of all adult enrollees reported they had developed new asthma, 16% likely had posttraumatic stress disorder (PTSD), and 8% had severe psychological distress. The rate of new asthma was highest (6%) among rescue and recovery workers who worked on the debris pile on 9/11, while the PTSD rate was highest among injured (35%), low-income (31%) and Hispanic (30%) enrollees. In general, minorities and low-income enrollees experienced higher rates of mental and physical problems, as did women. "The health impact of 9/11 reached far beyond the deaths and injuries that occurred that day," said Lorna Thorpe, Deputy Commissioner for Epidemiology at the Health Department. "But many of the health issues that have emerged, such as asthma and PTSD, are treatable. Free treatment is available. Anyone still in need of help should call 311 or visit nyc.gov." While it is difficult to pinpoint the total number of people sickened by the 9/11 attacks of the World Trade Center, the new analysis includes estimated ranges. Slightly more than 400,000 people were heavily exposed to the disaster based on registry criteria. The new data suggest that 35,000 to 70,000 people developed PTSD, and 3,800 to 12,600 people may have developed asthma as a result of 9/11. Two to three years after the event, 3% of Lower Manhattan adult residents and workers had developed asthma, according to the new analysis - twice what is believed to be the baseline rate of development of asthma over that period. Asthma was more prevalent among adult residents who did not evacuate on 9/11 (3.7%), or who returned to homes within two days (3.6%), compared to those who stayed away until December (2%). The same pattern was seen among downtown workers who returned within days of the disaster (3.5%) and passersby who happened to be in lower Manhattan the morning of the attacks (3.6%). Rates among all three groups are similar to those previously published for rescue and recovery workers and volunteers. Past findings have shown elevated PTSD rates among adult residents of Lower Manhattan, but the new findings provide additional insight. Residents and downtown workers who couldn't - or wouldn't - return to lower Manhattan for months after the attacks reported higher PTSD rates than those who did not evacuate (20% or higher for both). Both findings are expected because PTSD sufferers tend to avoid the site of their traumatic experience. "These data show that rescue and recovery workers were not the only groups affected," said Dr Mark Farfel, Director of the World Trade Center Health Registry. "Living and working near the WTC site also put people at risk of health problems." Farfel M, Digrande L, Brackbill R, et al. An Overview of 9/11 Experiences and Respiratory and Mental Health Conditions among World Trade Center Health Registry Enrollees. J Urban Health. 2008 Sep 11 [Abstract] (Source: Latest entries from www.anxietyinsights.info) by Malaysian Medical Resources 18 Aug 2008 at 10:00pm Arthritis Vaccine in Development, Boys More Likely to Shed Asthma Symptoms, FDA Considers Bisphenol A Safe Another Insidermedicine update for you…. a Arthritis Vaccine in Development, Boys More Likely to Shed Asthma Symptoms, FDA Considers Bisphenol A Safe (Source: Malaysian Medical Resources) by Healthbolt 26 Jul 2008 at 9:50am It’s summer in the Northern Hemisphere, and with summer comes all kinds of storms. And all kinds of opportunities for allergies. Here’s something you may have never thought of, though: you may be allergic to thunderstorms. Yeah, for real. If you suffer from allergies or asthma, keep an eye to the sky and an ear on the weather reports, since the pollen and mold spores that are sucked into the cloud base at the start of a storm can be broken down into even smaller particles and inhaled even more easily, triggering attacks or flare-ups. The fix? When a storm’s a-brewing, head inside and shut the windows since the greatest risk is at the onset of a storm. Pregnant with asthma? Check out Marijke’s post at Womb Within for ideas on asthma medications. Tags: allergies, Asthma, Health Issues from Storms, Healthbolt, StormsShare This (Source: Healthbolt) by Latest entries from www.anxietyinsights.info 19 Jun 2008 at 2:54am Moving house or the separation of parents may significantly increase the risk of children developing allergies later on according to results from a long-term study correlating life-style, immune system development and allergies. Stress events during childhood are suspected of playing a role in the later development of asthma, allergic skin disorders, or allergic sensitizations. Dramatic life events such as the death of a family member, serious illnesses of a family member or the separation of parents, but also harmless events like for example moving house are suspected of increasing the risk of allergies for the children affected. While a link between stressful events and the development of allergies has been known for some time, the mechanisms behind this remained unexplained. The immune system is thought to be a mediator role between stress on the one hand and allergies on the other so Dr Gunda Herberth and colleagues from the Helmholtz Center for Environmental Research in Leipzig (UFZ), the Helmholtz Zentrum München and the Institut für Umweltmedizinische Forschung (IUF) in Duesseldorf, Germany attempted to identify stress-related factors showing an influence on the immune system, using data from the Lifestyle - Immune System - Allergy (LISA) epidemiological study. They also examined blood samples taken from 234 six-year old children and discovered increased blood concentrations of the stress-related peptide VIP (vasoactive intestinal polypeptide) in connection with moving house or the separation of parents. Neuropeptide VIP could take on the mediator role between stress events in life and the regulation of immune responses, the researchers write in the scientific journal Pediatric Allergy and Immunology. Together with colleagues from the Institute for Social Medicine at the University of Lübeck the researchers also analyzed the most diverse social factors in the children's environment, in order to discover which factors were causing stress-related regulation deficiencies of the immune system. In children whose parents had separated over the last year the researchers found not only increased blood concentrations of neuropeptide VIP but also increased concentration of immune markers which are related to the occurrence of allergic reactions such as the cytokine IL-4. By comparison, serious illness or the death of close relatives produced no significant changes. Likewise, the unemployment of parents was not associated with increased concentrations of the stress-related peptides. As tragic as these events are, they appear less significant in terms of the children's stress reactions than, for example, a separation or the divorce of parents, the researchers concluded. As was already shown in an earlier results [1, 2], increased stress peptide VIP concentrations can also be found in the blood of children after moving house (similar to the separation of parents). An earlier analysis of the LISA data found there is a relationship between an increased neuropeptide VIP concentrations and allergic sensitizations among six-year old children. While those results were not conclusive because of the comparatively small number of children affected, they nevertheless provide valuable indications as to what happens in the body through stress. The LISA study investigates the influences of lifestyles on immune system development in early childhood and the emergence of allergies. For the study over 3000 newborn children in the cities of Munich, Leipzig, Wesel and Bad Honnef, Germany were recruited between the end of 1997 and the beginning of 1999. Parents were repeatedly asked about various lifestyle-related factors and disease outcomes. Furthermore, blood tests were carried out at different times. At the age of six a total of 565 children were examined and blood analyses of stress and immune parameters were carried out on 234 of these. Over the course of the 6-year study nearly one third of the families living in Leipzig were affected by unemployment. About half of all families experienced severe illnesses in close family members. Cases of death among family members or the separation of parents were less common affecting 10 to 16 percent of the children. Herberth G, Weber A, Röder S, et al. Relation between stressful life events, neuropeptides and cytokines: an epidemiological study. Pediatr Allergy Immunol. 2008; doi:10.1111/j.1399-3038.2008.00727.x [Abstract] (Source: Latest entries from www.anxietyinsights.info) by Pharmalot 12 Jun 2008 at 7:45am For the past few years, safety questions have hovered over Advair, a long-acting beta agonist that includes a steroid and a $6 billion seller. An FDA alert was issued in 2005; last November, an FDA panel recommended more warnings for kids both Advair and Glaxo’s Serevent, which doesn’t include a steroid; and the agency asked drugmakres for more data as a prelude to an advisory committee meeting later this year. In an attempt to get out in front of the controversy, Glaxo sponsored a review in the Annals of Internal Medicine shows that Advair decreases the risk of severe side effects, doesn’t appear to alter the risk for hospitalization, and may not change the risk for asthma-related deaths when compared with the use of steroids alone. In reaching this conclusion, the researchers conducted a meta-analysis of 66 trials involving a total of 20,966 patients. However, in an accompanying editorial by Kevin Weiss says the review is well done, but the source of the data - randomized efficacy trial - limits its ability to answer a key question: Does the use of long-acting beta-agonists combined with inhaled steroids enhance effeciveness and reduce risks? Weiss - a Northwestern University professor, ceo of the non-profit American Board of Medical Specialties, and a Merck asthma consultant - says the researchers tripped up by mixing Glaxo’s SMART study, a large, prospective, real-world clinical trial, with several smaller trials for closely supervised patients. He also writes that major adverse event rates were higher in SMART, suggesting samples were different; different attention levels were given to measuring adversing events, or both. And the meta-analysis didn’t address higher mortality rates in African-Americans. And so, Weiss concludes, the study may have “ultimately helped answer the question about safety when long-acting beta-agonists are used with inhaled steroids in an idealized clinical environment, but they did not resolve the controversy about the safety of long-acting beta-agonists (with or without steroids) in an environment that more closely reflects actual clinical practice.” By the way, GlaxomithKline supported data collection, analyses, manuscript preparation, and data interpretation, while the authors say approved the manuscript for submission. Four of seven authors are Glaxo employees. The lead author, Eric Bateman, is a Glaxo consultant, has done speaking for Glaxo, received Glaxo grants and provided expert testimony for Glaxo in trials. Here is the dislcosure info. (Source: Pharmalot) by Dr. Z's Medical Report 4 Jun 2008 at 5:06pm I don’t really know if Lindsay Lohan had an asthma attack at 30,000 feet, or whether she spent two hours in an LA emergency room or had to be admitted for treatment, because the news reports are conflicting and unclear as of this writing. But I do know that millions of Americans suffer acute asthma attacks every year (11 million during each year between 1997 and 2004), and that they often require emergency room treatment (1.8 million asthma ER visits for each year between 2001 and 2003) and hospitalization (an average of 500,000 hospital admissions each year). Worse yet, there were about 4,200 deaths from asthma each year between 2001 and 2003. Those alarming statistics come from the Centers for Disease Control (CDC). What these numbers mean is that a lot of people depend on albuterol-based rescue inhalers to treat their acute asthma symptoms (as well as people with chronic obstructive pulmonary disease, or COPD). And on May 30, 2008, the FDA issued a public health advisory to inform rescue inhaler users that they must switch from CFC-containing inhalers to the more environmentally friendly HFA inhalers by year’s end, because the former will no longer be sold as of January 1, 2009. Because this changeover is so important, I’ve written about it before – and HealthTalk produced a webcast about it as well: Planning Ahead to Replace Banned Asthma Inhalers. The older inhalers contained chemicals called chlorofluorocarbons (CFCs) to propel the albuterol from the inhaler into your lungs. It was discovered many years ago, however, that CFCs are bad for the ozone layer in the atmosphere, and because of this their use was banned in just about everything but asthma inhalers. Now the law is finally being expanded to prevent the sale of CFC-containing inhalers beginning in 2009. They are to be replaced with inhalers containing a chemical propellant called hydrofluroalkane (HFA), which does not deplete the ozone. Already, there are three approved HFA-propelled albuterol inhalers: Proair, Proventil and Ventolin. In addition, an HFA-propelled inhaler containing levalbuterol, a medicine similar to albuterol, is available as Xopenex HFA Inhalation Aerosol. According to the FDA, “HFA-propelled albuterol inhalers may taste and feel different than the CFC-propelled albuterol inhalers. Notably, the force of the spray of an HFA-propelled inhaler may feel softer than that of a CFC-propelled inhaler. It is important to prime and clean the HFA propelled inhalers to prevent blockage in the inhaler device that will prevent the medicine from reaching the lungs. Each HFA-propelled inhaler has different priming, cleaning and drying instructions. Therefore, it is important to read and understand the instructions that come with each of the HFA-propelled albuterol inhalers before using.” You can read the entire FDA public health advisory, National Transition from Chlorofluorocarbon (CFC) Propelled Albuterol Inhalers to Hydrofluroalkane (HFA) Propelled Albuterol Inhalers. If you haven’t made the transition from CFC- to HFA-propelled albuterol inhalers, you need to make a doctor’s appointment now. Don’t wait until it’s too late and your doctor is backed up and the pharmacy’s run out of new inhalers, which may happen towards year end. -Ed (Source: Dr. Z's Medical Report) by Dr. Z's Medical Report 3 Jun 2008 at 1:44pm I don’t really know if Lindsey Lohan had an asthma attack at 30,000 feet, or whether she spent two hours in an LA emergency room or had to be admitted for treatment, because the news reports are conflicting and unclear as of this writing. But I do know that millions of Americans suffer acute asthma attacks every year (11 million during each year between 1997 and 2004), that they often require emergency room treatment (1.8 million asthma ER visits for each year between 2001 and 2003), and hospitalization (an average of 500,000 hospital admissions each year). Worse yet, there were about 4,200 deaths from asthma each year between 2001 and 2003. Those alarming statistics come from the Centers for Disease Control (CDC). What these numbers mean is that a lot of people depend on albuterol-based rescue inhalers to treat their acute asthma symptoms (as well as people with chronic obstructive pulmonary disease or COPD). And on May 30, 2008, the FDA issued a public health advisory to inform rescue inhaler users that they must switch from CFC-containing inhalers to the more environmentally friendly HFA inhalers by year’s end because the former will no longer be sold as of January 1, 2009. Because this changeover is so important, I’ve written about it before and HealthTalk produced a webcast about it as well, “Planning Ahead to Replace Banned Asthma Inhalers.” The older inhalers contained chemicals called chlorofluorocarbons (CFCs) to propel the albuterol from the inhaler into your lungs. It was discovered many years ago, however, that CFCs are bad for the ozone layer in the atmosphere and because of this their use was banned in just about everything but asthma inhalers. Now the law is finally being expanded to prevent the sale of CFC-containing inhalers beginning in 2009. They are to be replaced with inhalers containing a chemical propellant called hydrofluroalkane (HFA), which does not deplete the ozone. Already there are three approved HFA propelled albuterol inhalers: Proair HFA Inhalation Aerosol, Proventil HFA Inhalation Aerosol, and Ventolin HFA Inhalation Aerosol. In addition, an HFA propelled inhaler containing levalbuterol, a medicine similar to albuterol, is available as Xopenex HFA Inhalation Aerosol. According to the FDA, “HFA propelled albuterol inhalers may taste and feel different than the CFC propelled albuterol inhalers. Notably, the force of the spray of an HFA propelled inhaler may feel softer than that of a CFC propelled inhaler. It is important to prime and clean the HFA propelled inhalers to prevent blockage in the inhaler device that will prevent the medicine from reaching the lungs. Each HFA propelled inhaler has different priming, cleaning, and drying instructions. Therefore, it is important to read and understand the instructions that come with each of the HFA propelled albuterol inhalers before using.” You can read the entire FDA public health advisory titled, “National Transition from Chlorofluorocarbon (CFC) Propelled Albuterol Inhalers to Hydrofluroalkane (HFA) Propelled Albuterol Inhalers.” If you haven’t made the transition from CFC to HFA-containing albuterol inhalers, you need to make a doctor’s appointment now. Don’t wait until it’s too late and your doctor is backed up and the pharmacy’s run out of new inhalers, which may happen towards year end. (Source: Dr. Z's Medical Report) by Genetics and Health 23 May 2008 at 4:22am (Image credit www.about.com) A University of Carolina study monitoring 1200 newborns found that first borns were more likely to carry a gene variant which raised their risk of developing an allergy before the age of 10. The study suggested that a first born experienced different conditions in the uterus from subsequent siblings. The researchers measured levels of an antibody called Immunoglobulin E (IgE) in the babies’ umbilical cord blood. This is known to play a key role in the development of allergic responses. First born babies were more likely to have high levels of IgE, and those that did were also more likely to show signs of an allergic response when they were subsequently tested, using a skin prick test, at the age of four and ten. The researchers also believe they may have pinned down the genetics behind the difference to variations in a gene called IL13, which controls production of a stress hormone called a cytokine, which in turn influences levels of IgE. They found that first born children were more likely to carry a variant of IL13 which raises levels of the cytokine, and in turn IgE. The researchers believe that birth order may affect expression of the gene during the foetal differentiation and development. Lead researcher Dr Wilfried Karmaus said: “We were not surprised that birth order had an effect on the development of the immune system, but were surprised that this interaction persisted at least through age ten … Our findings add to the evidence that allergic reactions are programmed during pregnancy and then effect the disease in later life. … This finding may partially account for the increasing prevalence of asthma and allergies in children in the last 30 years, primarily seen in the western world, as developed nations’ birthrates continue to decline.” He said that if a way to modify those conditions could be found to make them more like those experienced by later born children, then potentially it might be possible to prevent 20-30% of all cases of asthma and allergy. Elaine Warburton www.geneticsandhealth.com Tags: Allergies, allergy, asthma, Genes, Genetic risk, Genetic Testing, Genetics of Disease, hayfeverShare This (Source: Genetics and Health) by Latest entries from www.anxietyinsights.info 19 May 2008 at 2:18am Women who are psychologically stressed during pregnancy may pass some on to their fetuses in the form of increased sensitivity to allergen exposure and possibly future asthma risk, according to researchers from Harvard Medical School who presented their findings at the American Thoracic Society's 2008 International Conference in Toronto on Sunday. "While predisposition to asthma may be, in part, set at birth, the factors that may determine this are not strictly genetic. Certain substances in the environment that cause allergies, such as dust mites, can increase a child's chance of developing asthma and the effects may begin before birth," said Rosalind J. Wright, M.D., MPH, assistant professor of medicine at Brigham & Women's Hospital and Harvard Medical School. Mother's stress during pregnancy can also influence the babies developing immune system. While animal studies suggest that the combination of stress and allergen exposure during pregnancy may magnify the effects on the immune system, this is the first human study to examine this directly. The researchers analyzed levels of maternal stress and mother's exposure to dust mite allergen in their homes while pregnant with respect to cord blood IgE expression - a marker of the child's immune response at birth - in 387 infants enrolled in the Asthma Coalition on Community, Environment, and Social Stress (ACCESS) project in Boston. They found increased levels of IgE expression in cord blood among infants whose mothers experienced higher level stress even when exposed to relatively low levels of dust mite during pregnancy. This indicates that mother's stress during pregnancy magnified the effect of dust exposure on the fetus's immune system such that the baby's immune response at birth may be altered even with lower levels of dust exposure in the home. The results held true regardless of the mother's race, class, education or smoking history. "This research adds to a growing body of evidence that links maternal psychological stress such as that precipitated by financial problems or relationship issues, to changes in children's developing immune systems, even during pregnancy," said Dr Wright. "This further supports the notion that stress can be thought of as a social pollutant that, when 'breathed' into the body, may influence the body's immune response similar to the effects of physical pollutants like allergens, thus adding to their effects." While these findings are important, Dr Wright noted that only with continued follow-up of these children will they know if these effects will result in increased asthma risk. Moreover, it will be important to replicate these findings in larger populations to give a clearer picture of the relationship between prenatal maternal stress, allergen exposure and subsequent childhood asthma development. "It is notable that these findings were obtained in a U.S. urban population, which may be more likely to be simultaneously exposed to multiple factors, including stress and indoor allergens. More studies like this may help explain why asthma occurs more frequently in these high-risk groups," said Junenette Peters, Sc.D., postdoctoral research fellow who presented these results. In the meantime, the findings suggest that when such exposures - prenatal stress, allergen exposure - occur together, there is a magnified increase in risk, which supports the assessment of maternal psychological well-being along with other environmental factors as part of a prenatal health program. Peters J, Suglia SF, Platts-Mills TAE, et al. Psychological Stress Modifies the Influence of Prenatal Allergen Exposure on Cord Blood IgE: The Boston ACCESS Project. Mini-Symposium A92, ATS Int Conf, Toronto 2008 May 18 [Abstract] (Source: Latest entries from www.anxietyinsights.info) by Dr. Z's Medical Report 15 Apr 2008 at 2:34pm This year marks the 10th anniversary of World Asthma Day, which occurs on Tuesday, May 6, 2008. It is organized by the Global Initiative for Asthma (GINA), in collaboration with healthcare groups and asthma educators to raise awareness about asthma and improve asthma care throughout the world. This year’s theme is “You Can Control Your Asthma.” Asthma control is the goal of treatment and can be achieved in the vast majority of asthma patients with proper management. A person’s asthma is under control when he or she has: • No (or minimal) asthma symptoms. • No waking at night due to asthma. • No (or minimal) need to use “reliever” medication. • The ability to do normal physical activity and exercise. • Normal (or near-normal) lung function test results (PEF and FEV1). • No (or very infrequent) asthma attacks. If your asthma isn’t under control, you should see your doctor and discuss ways to bring it in line. It may be that you have untreated allergies. It may be that you need better to identify and then avoid environmental triggers. You may need different medication, such as a long-term controller medicine as opposed to simply using a rescue inhaler. Speaking of rescue inhalers, everyone who uses such products needs to know about the major changes now occurring with them. At the end of 2008, no inhaler containing CFCs (the ozone-depleting chemicals called chlorofluorocarbons) can be legally manufactured in the United States. While there may still be some inventory left at the end of the year, it is critical that all people using CFC-containing inhalers be switched to the newer HFA-containing inhalers and that they do it sooner rather than later (avoiding a year-end emergency). Many years ago it was recognized that CFCs were destroying the ozone layer and so the vast majority of these chemicals were banned. The one holdout was for the asthma inhalers so that research could be done to develop new products. Now it’s time for the CFC-containing inhalers to go the way of all other CFC-containing products; namely, away. The laws are written, the new products are being made and many asthma patients have already switched. This is a done deal and you need to get with the program (to use two clichés). If you use a rescue inhaler, such as an albuterol inhaler, and you haven’t already seen your doctor to switch, make an appointment today. Because of the importance of this change, HealthTalk produced a webcast on March 20, 2008 entirely devoted to the topic. You can listen to the replay and you can read a news report on the webcast. The new HFA inhalers are just as effective as the older CFC inhalers, but they are different. For one thing, they are more expensive. Another is that the puff of medication is less forceful than with the older inhalers. People may be so used to the force of the old inhalers that they believe the new ones are less effective. This isn’t true and you’ll need time to adjust to the new feel and get proper instructions from your doctor. (Source: Dr. Z's Medical Report) by World of Psychology 27 Mar 2008 at 7:41pm No, not yet. But the U.S. Food and Drug Administration (FDA) today notified the maker of Singulair, a popular drug used to treat asthma, that it wanted more information and data about its use and suicide and suicidal thoughts. According to a report at WebMD, “In response to inquiries received by the FDA, the FDA has asked Merck to evaluate Singulair study data for more information about suicidality and suicide. The FDA is also reviewing its postmarketing reports of behavior/mood changes, suicidality, and suicide in patients who took Singulair.” In a statement, Merck said its analysis of more than 11,000 patients in 40 clinical trials of Singulair found no reported suicides or suicidal thoughts or behavior. You can read more about the issue from this Reuters report on the FDA’s request about Singulair and suicide. (Source: World of Psychology) by Fade Library 26 Mar 2008 at 9:53am Antenatal care Diabetes in pregnancy Prophylaxis for Infective Endocarditis Maternal and child nutrition Mental wellbeing of children in primary education Sleep apnoea hypopnea syndrome (obstructive) - continuous positive airway pressure Asthma (in adults) - corticosteroids Intraoperative nerve monitoring during thyroid surgery Suburethral sling insertion for stress urinary incontinence in men (Source: Fade Library) by PharmaGazette 5 Feb 2008 at 9:00am Schering-Plough Corp (NYSE:SGP) announced that the U.S. Food and Drug Administration has approved its once-a-day asthma corticosteroid inhaler for children. The inhaled steroid for the prevention of asthma attacks can be used with children as young as 4.Asmanex Twisthaler received FDA approval two years ago as a maintenance treatment to prevent flare-ups in adults and children over the age of 12. The dosage for children under 12 is roughly half the adult dosage of 220 micrograms. While other asthma product exisit for young children all must be taken more often throughout the day.The unique aspect of the Twisthaler is that it does not have a propellant like other inhalers. It is activated as the patients inserts the inhaler into their mouth and inhales. A counter on the product keeps track of the remaining doses.Asmanex Twisthaler has similar side effects to other corticosteroid inhalants such as stunted growth, fungal infections of the mouth, and an increased risk of glaucoma or cataracts. The more common side effects include headaches, sore throat, muscle, bone and back pain, respitory infections or upset stomach.Schering expects the Asmanex Twisthaler to be available to children 4 - 11 years of age in the second half of 2008.[Source: YahooNews] (Source: PharmaGazette) by Pharmalot 4 Feb 2008 at 5:29pm And so Monday is over. Hope yours was as interesting as ours. Now, though, the time has come to catch up on sundry tasks - recycling, for instance, must be carted off the Pharmalot corporate campus this evening - and we hope to indulge later with a good book. See you all in the morning… Schering-Plough Asthma Inhaler Approved For Children (Yahoo/AP) Glaxo Vaccine May Prevent Recurrence Of Lung Cancer After Surgery (The Telegraph) Three Pfizer Employees In Nigerian Court In Trovan Case (Agence France Presse) (Source: Pharmalot) |
6 Oct 2008 at 5:56pm ... habits are a contributing factor in dramatic increases in childhood obesity, type 2 diabetes, asthma and high cholesterol. The Centers for Disease Control and Prevention says the number of ... 6 Oct 2008 at 5:38pm ... often simple things we can do to protect children from environmental hazards, including avoiding asthma triggers such as secondhand smoke or mold. October is Children's Health Month. Qu hace ... 6 Oct 2008 at 5:31pm ... said Heron, who the court heard suffers from a range of illnesses including diabetes, asthma and hypertension, became involved in the crime to alleviate suspicion. She said: "I have ... 6 Oct 2008 at 5:29pm ... said Heron, who the court heard suffers from a range of illnesses including diabetes, asthma and hypertension, became involved in the crime to alleviate suspicion. "I have no doubt ... 6 Oct 2008 at 5:16pm ... also may have some beneficial effects, including possible roles in reducing diarrheal diseases and asthma, Kamangar said. For the study, Kamangar and co-author Farhad Islami of the University of ... 6 Oct 2008 at 5:05pm ... their children into clinics often received free samples for drugs such as Advair for asthma; Adderall and Strattera, for attention deficit disorder; and Elidel, for eczema. Free samples can ... 6 Oct 2008 at 5:00pm ... imaginable. Our expert Guides offer information and tutorials on hundreds of topics, ranging from asthma to action movies, home repair to home cooking, gadgets to getaways. As a Guide ... 6 Oct 2008 at 4:59pm ... six children between the ages 2 and 19 is overweight, a risk factor for asthma, diabetes and heart disease. Officials said in the last 30 years obesity has doubled ... 6 Oct 2008 at 4:58pm ... the development of such conditions as autism, cerebral palsy, learning disabilities, birth defects, diabetes, asthma, and obesity. Throughout its 25-year span, the study is expected to shed light on ... 6 Oct 2008 at 4:58pm ... children from before birth to age 21, tracking information on topical health issues including asthma, birth defects, diabetes, heart disease and obesity. (PressZoom) - DALLAS Oct. 3, 2008 ... 6 Oct 2008 at 4:58pm ... at Canterbury crown court, the judge, Adele Williams, described Heron - who has diabetes, asthma and hypertension - as a "willing participant" in the crime. "I have no doubt ... 6 Oct 2008 at 4:37pm ... Williams said Heron, who the court heard suffers from a range of including diabetes, asthma and hypertension, became involved in the crime to alleviate suspicion. She said: "I have ... 6 Oct 2008 at 4:34pm ... habits are a contributing factor in dramatic increases in childhood obesity, type 2 diabetes, asthma and high cholesterol. The Centers for Disease Control and Prevention says the number of ... 6 Oct 2008 at 4:34pm ... at Canterbury crown court, the judge, Adele Williams, described Heron - who has diabetes, asthma and hypertension - as a "willing participant" in the crime. "I have no doubt ... 6 Oct 2008 at 4:33pm ... clips feature children, parents discussing clinical studies BETHESDA, Md., Oct. 6 /PRNewswire-USNewswire/ -- From asthma and cancer treatments to vaccines, research in children saves lives and improves their health ... |
6 Oct 2008 at 4:14pm A ground-breaking study has found that getting rid of unflued gas heaters can reduce the cost of treating asthma symptoms by about as much as the millions of dollars the country spends every year on new asthma ... 6 Oct 2008 at 8:12am Washington, Oct 6 : A new study has revealed that asthmatic kids whose parents have high expectations for their ability to function normally are less likely to have symptoms than other children dealing with the ... 5 Oct 2008 at 8:05am Synairgen has selected Exco InTouch's eDiary solutions to capture ePRO data in its IFN-beta Asthma Trial 2008-09-30 14:51:17 - Exco InTouch's Electronic Patient Diary Selected by Synairgen to Capture ePRO Data ... 4 Oct 2008 at 7:53am Ever since the huge windstorm blew into Kentuckiana, Allergy and Asthma symptoms are causing widespread misery. 3 Oct 2008 at 11:41pm Young children who wheeze when they have rhinovirus infection - the most common cause of colds - are at much greater risk of developing asthma later during childhood, a new study says. 3 Oct 2008 at 3:26pm Having asthma doesn't necessarily mean an unhealthy pregnancy. The key is to control symptoms and prevent attacks. 3 Oct 2008 at 7:03am SYDNEY, Australia, Oct. 3 Pharmaxis-research SYDNEY, Australia , Oct. 3 /Xinhua-PRNewswire-FirstCall/ -- Pharmaceutical company Pharmaxis has announced that researchers will present 12 abstracts from its ... 2 Oct 2008 at 8:44pm The inhaled steroids that are often used to treat asthma don't work as well in the overweight or obese, new research shows. 2 Oct 2008 at 4:29pm NEW YORK (Reuters Health) - Lab experiments indicate that people with asthma who are overweight or obese have a reduced response to steroid treatment, compared with their lean counterparts. Inhaled steroids are the mainstay of asthma treatment, because they reduce airway inflammation that can lead to an asthma attack. "This study identifies what could be a significant issue for the 20 million Americans with asthma; specifically, the main controller medication might be less effective if you are overweight or obese," lead author Dr. E. Rand Sutherland, from National Jewish Medical and Research Center in Denver, said in a statement. 1 Oct 2008 at 4:11pm Glucocorticoids, the primary controller medication for asthma, are 40 percent less effective in overweight and obese asthma patients than in those of normal weight, according to researchers at National Jewish ... 1 Oct 2008 at 7:49am Main Category: Respiratory / Asthma Also Included In: Medical Students / Training In combination with conventional management and assessment of asthma patients, the measurement of exhaled nitric oxide does not ... 1 Oct 2008 at 3:29am Asthma that manifests in early adulthood has its origins in early childhood, according to an article released on September 19, 2008 in The Lancet . 30 Sep 2008 at 5:51am About 20 million Americans suffer from asthma, and it's getting even more prevalent. 29 Sep 2008 at 5:31am Michelle Morris was a young child when she was diagnosed with asthma and had to learn the signs and symptoms of the chronic disease. 28 Sep 2008 at 7:04am Preventive measures can offer much-needed hope in the battle against asthma. THE prevalence of asthma has increased dramatically in industrial countries, including Malaysia, in the last 20 years. |
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